Bisdimedone derivatives were synthesized by the method adopted by Horning and Honing. All the newly synthesized compounds showed antimicrobial activities against certain bacterial and fungal strains. The compounds 2-(2-chloro-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)-methylfuran and 2-(4-flor-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)methylfuran showed good activity against Proteus mirabilis and Klebsiella pneumonia and 2-(4-chloro-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)-methylfuran and 2-(2-chloro-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)-methylfuran showed prominant activity against Staphylococcus aureus. Bisdimedone derivatives shows fungicide activity as well.
A Wani, M., A Farooqi, J., & A Shah, W. (2016). Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives. Journal of Pharmaceutical and Applied Chemistry, 2(2), 89-93. doi: 10.18576/jpac/020204
MLA
Mukhtar A Wani; Javeed A Farooqi; Wajahat A Shah. "Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives". Journal of Pharmaceutical and Applied Chemistry, 2, 2, 2016, 89-93. doi: 10.18576/jpac/020204
HARVARD
A Wani, M., A Farooqi, J., A Shah, W. (2016). 'Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives', Journal of Pharmaceutical and Applied Chemistry, 2(2), pp. 89-93. doi: 10.18576/jpac/020204
VANCOUVER
A Wani, M., A Farooqi, J., A Shah, W. Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives. Journal of Pharmaceutical and Applied Chemistry, 2016; 2(2): 89-93. doi: 10.18576/jpac/020204
)
View on SCiNiTO