Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient

Adeyanju, O.; Ewaoche, E. A.; Plavec, J.

doi:10.18576/jpac/030303

Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient

Document Type : Original Article

Authors

¹ Department of Chemistry, Faculty of Natural Sciences, University of Jos, Nigeria.

² Department of Pharmaceutical technology, Faculty of Pharmaceutical Sciences, University of Jos, Nigeria.

³ National Institute of Chemistry, NMR Centre, Ljublijana, Slovenia.

10.18576/jpac/030303

Abstract

Oxidized S.mycrophylla gum was prepared,characterized by FTIR, XRD, SEM, EDX and evaluated for its physicochemical characteristics. Oxidized gum showed improved physicochemical parameters, than the native gum with moisture content to be 3.5±40.10%. Ash 1.98±0.25%, protein 1.04 ± 0.05%, pH 4.95± 0.25, viscosity (CS), 56.32±6.79, refractive index 1.33±0.02, water holding capacity 94:63 ±8.45%, specific rotation - 15.2±0.09 degree Celsius,Emulsifying capacity 48.03±4.65cm-1 and swelling index 25.36±2.64%. Chemical modification via oxidation increased the physicochemical properties of the native gum. The experimental work, provide enough evidence to exploit this natural biopolymer in food and pharmaceutical formulations..

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