The Relation between Hypothyroidism and Polycystic Ovary Syndrome

Document Type : Original Article


1 Department of Chemistry (biochemistry), Faculty of Science, Ajdabiya University, Libya

2 OB& Gynecology, BMC, Benghazi, Libya.

3 Department of Chemistry (biochemistry), Faculty of Science, Benghazi University, Libya.



Polycystic ovarian syndrome (PCOS) is the most common reproductive disorder, affecting up to 12 percent of all women. It is a disorder with many different faces, and it causes great emotional and physical distress to the millions of women worldwide who suffer from it. There’s a significant overlap of symptoms between PCOS and Thyroid Disease, despite the fact that they are two very different conditions. This study measures the levels of TSH, T3, T4, FSH, LH and E2 in females suffering from polycystic ovarian syndrome (PCOS). The prevalence of TSH, LH and E2 are all significantly higher than those in healthy women. Level of FSH and T3 almost remained normal in polycystic ovarian syndrome. While the T4 slightly decreased in PCOS cases as compared with healthy control group. The data revealed that the patients of PCOS were found to be suffering from hypothyroidism as was evident by increased TSH and LH to FSH ratio. Thus ,thyroid profile analysis may help in providing a better insight into symptomatology and treatment of PCOS.