Chemistry Department, Faculty of Science, Sohag 82524, Egypt.
10.12785/jpac/010202
Abstract
A new series of fused heterocyclic compounds containing pyridine moieties were prepared via the reaction of 2-amino-6-(methylthio)-4-phenylpyridine-3,5-dicarbonitrile with some halo reagents, active methylenes, acetic anhydride, phenylisothiocyanate, hydrazine hydrate or thioacetamide. Accompanied with Predictions of the activity spectra of some selected compounds using PASS INET.at Pa > 70%, showing high probability of Atherosclerosis treatment, Antineoplastic, DNA intercalator, Protein kinase inhibitor and Signal transduction pathways inhibitor.
El-Sayed, A. M., Abdel-Ghany, H., Amer, A. A., & Ahmed., A. M. (2015). Synthesis of Some New Fused Pyridines and Prediction their Biological Activity via PASS INET.. Journal of Pharmaceutical and Applied Chemistry, 1(2), 28-34. doi: 10.12785/jpac/010202
MLA
A. M. El-Sayed; H. Abdel-Ghany; A. A. Amer; A. M. Ahmed.. "Synthesis of Some New Fused Pyridines and Prediction their Biological Activity via PASS INET.", Journal of Pharmaceutical and Applied Chemistry, 1, 2, 2015, 28-34. doi: 10.12785/jpac/010202
HARVARD
El-Sayed, A. M., Abdel-Ghany, H., Amer, A. A., Ahmed., A. M. (2015). 'Synthesis of Some New Fused Pyridines and Prediction their Biological Activity via PASS INET.', Journal of Pharmaceutical and Applied Chemistry, 1(2), pp. 28-34. doi: 10.12785/jpac/010202
VANCOUVER
El-Sayed, A. M., Abdel-Ghany, H., Amer, A. A., Ahmed., A. M. Synthesis of Some New Fused Pyridines and Prediction their Biological Activity via PASS INET.. Journal of Pharmaceutical and Applied Chemistry, 2015; 1(2): 28-34. doi: 10.12785/jpac/010202
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