Green Chemistry Approach for Efficient Synthesis of Some New Spiro [Indoline- 3,4'-Pyran] Derivatives and Prediction their Biological Activity by PASS INET

Document Type : Original Article

Authors

1 Department, Faculty of Science, Sohag University, Sohag, 82524, Egypt

2 Chemistry Department, Faculty of Science, Minia University, El Minia 61511, Egypt.

3 Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt.

10.12785/jpac/010201

Abstract

Some new spiro compounds have been synthesized by reaction of isatin with different nucleophiles containing
activemethylene compounds. Their chemical structures have been confirmed by IR, 1HNMR and by elemental analysis.

Keywords